1 00:00:05,990 --> 00:00:03,429 hello 2 00:00:08,390 --> 00:00:06,000 i'm peter from georgia tech and i will 3 00:00:10,150 --> 00:00:08,400 present protovision a web-based tool for 4 00:00:12,150 --> 00:00:10,160 the concerted study of sequence 5 00:00:13,589 --> 00:00:12,160 alignments and structures 6 00:00:16,070 --> 00:00:13,599 in the study 7 00:00:19,510 --> 00:00:16,080 of the origin of life we often compare 8 00:00:21,670 --> 00:00:19,520 sequences of extent species 9 00:00:22,710 --> 00:00:21,680 to learn about ancient evolutionary 10 00:00:24,710 --> 00:00:22,720 events 11 00:00:26,870 --> 00:00:24,720 protovision provides an easy and 12 00:00:32,150 --> 00:00:26,880 intuitive interface to study the 13 00:00:34,310 --> 00:00:32,160 evolution of proteins in 1 2 and 3d 14 00:00:36,389 --> 00:00:34,320 protovision provides a set of alignments 15 00:00:37,750 --> 00:00:36,399 for the most ancient molecular fossil 16 00:00:39,830 --> 00:00:37,760 the ribosome 17 00:00:42,389 --> 00:00:39,840 and it calculates a sequence 18 00:00:45,750 --> 00:00:42,399 conservation it allows for the download 19 00:00:48,229 --> 00:00:45,760 of these alignments and the download of 20 00:00:50,150 --> 00:00:48,239 images and the mapping of different 21 00:00:53,990 --> 00:00:50,160 types of calculated data from these 22 00:00:58,790 --> 00:00:56,069 protovision can calculate amino acid 23 00:01:01,430 --> 00:00:58,800 frequencies based on these alignments 24 00:01:02,709 --> 00:01:01,440 and it allows for the saving of these 25 00:01:06,630 --> 00:01:02,719 frequencies 26 00:01:08,630 --> 00:01:06,640 both as an image and as a data 27 00:01:11,590 --> 00:01:08,640 finally protovision allows the 28 00:01:13,590 --> 00:01:11,600 connection of the alignment to 29 00:01:15,910 --> 00:01:13,600 the structure 30 00:01:19,990 --> 00:01:15,920 and the mapping of the data of the 31 00:01:22,230 --> 00:01:20,000 calculated data on 2d and 3d 32 00:01:26,230 --> 00:01:22,240 prodivision allows the download of high 33 00:01:28,550 --> 00:01:26,240 fidelity images from these viewers and 34 00:01:30,069 --> 00:01:28,560 the use and their use in publication 35 00:01:32,230 --> 00:01:30,079 images 36 00:01:35,270 --> 00:01:32,240 protovision is available at